World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

IN VITRO ANTICANCER ACTIVITY OF PUNICA GRANATUM FRUIT JUICE EXTRACT AGAINST OVARIAN CANCER AND OSTEOSARCOMA CELL LINES

Priyanka N., Mohanraj M., Lokesh Sharan B., Maruthamuthu M., Prabu Narayanan K. and *Sakthi Abirami M.

ABSTRACT

The plant has a long history of numerous traditional and ethno botanical application in diverse cultures. Punica granatum (Lythraceae) is traditionally used for anti-fungal, antioxidant, antimicrobial, anti-cancer and anti- bacterial activity. In the present study, In vitro anticancer activity of acetone extract of pomegranate juice was carried out in PA-1 cell line and MG 63 cell line through MTT assay method. The IC50 value of Punica granatum fruit extract was found to be 50.91 for ovarian cancer cell line (PA-1) and 52.76 for osteosarcoma cell line (MG 63). This has concluded that the pomegranate juice extract possess anticancer effect on ovarian cancer and osteosarcoma cell line due to the presence of flavonoids.

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