World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Directory of Research Journals Indexing, Scholar Article Journal Index (SAJI), International Scientific Indexing ( ISI ), Scope Database, 

Abstract

EVALUATION OF ANTI-MITOTIC ACTIVITY OF INDOLE DERIVATIVE ON GERMINATING BENGAL GRAM SEEDS

L. Srividya, G. Kiran and Dr. A. Rama Narsimha Reddy*

ABSTRACT

Isatin and its analogs are versatile substrates, which can be used for the synthesis of numerous heterocyclic compounds. Isatin and its derivatives are used in organic synthesis and they are used in evaluating new product that possesses different biological activities. The synthetic versatility of Isatin derivatives has been draw the attention in several synthetic organic and medicinal chemists due to varied biological and pharmacological properties of such compounds. Literature survey revealed that isatin (1H-indole-2,3-dione) possesses diverse chemotherapeutic activities, such as anticancer (Gursoy and Karal, 2003), antiviral (Debra et al., 2006), anti-HIV (Pandeya et al., 1999a), anti-mycobacterial (Karal et al., 2007), antibacterial (Pandeya et al., 1999b), anti-inflammatory (Sridhar and Ramesh, 2001) and anticonvulsant (Verma et al.,2004). Among these properties, cytotoxic and antiproliferative activities of this moiety have been found to be interesting.

[Full Text Article]

BEST PAPER AWARDS

World Journal of Pharmaceutical and life sciences Will give best paper award in every issue in the from of money along with certificate to promote research .

Best Article of current issue

Download Article : Click here