World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Dr. Devashish R. Solapurkar*, Dr. Rajesh Shetty, Dr. Soumya Shetty, Dr. Sharon Coelho, Dr. Sonal Kale


Background: To assess the effects of In-Office vital bleaching procedure using Hydrogen Peroxide 35% on Enamel Sensitivity. Objective: To assess the effects of In-Office vital bleaching procedure using Hydrogen Peroxide 35% on Enamel Sensitivity. Data Source: Electronic search of PubMed, Google Scholar, Institutional Library and Research gate. Study Eligibility Criteria: The following criteria was used to select the studies on sensitivity of enamel due to in-office vital bleaching procedure using Hydrogen Peroxide. The inclusion criteria were studies in English or those having detailed summary in English, studies that provide information on sensitivity of enamel on bleaching. Studies that were published between 1st January 2000 till date. Clinical Trials were selected. The exclusion criteria were case reports, abstracts, letters to editors, editorials and in vitro studies. Studies that did not use Hydrogen Peroxide in in-office Vital Bleaching Procedure. Intervention: Hydrogen Peroxide was selected as the intervention with a specific concentration of 35%. Results: Various electronic databases were searched using different search strategies from the above mentioned key words and the combinations. The number of articles identified through the database searching were 226 in all. After thorough reading of tittles the number of articles found relevant were only 48. Further these records were assessed for any duplicates and 37 duplicate articles were removed whilst including 11 articles. Full text thorough reading of these 11 articles was done and were assessed for eligibility. Only 7 articles were qualified and 4 articles were excluded. Conclusions: The available evidence on this topic is scarce, and the findings of studies were not consistent. Additional randomized clinical trials using clinical outcomes to evaluate the sensitivity of enamel after bleaching with 35% Hydrogen Peroxide are needed.

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