Abstract
INTERACTION OF DRUG AND ALVEOLAR BONE – A REVIEW
Nidhi Tiwari, Himanshu Thukral, Rahul Kukreja, Bhawana Yadav, Sapna Saini, Shafaly Khurana, Vinita Dahiya
ABSTRACT
Bone is a unique tissue that constitutes the supporting skeletal framework of all higher vertebrates. It is a dynamic structure composed of an organic matrix (30-35%), inorganic calcium phosphate minerals (65-70%) and cells. The highly organized structure of bone at many length scales gives rise to diverse mechanical, biological and chemical functions; such as protection to vital organs, structural support and self-repairing properties. Moreover, bone is considered the main reservoir for calcium and phosphate ions and a wide range of cytokines and growth factors. Mechanical strength of bone is maintained throughout life by modeling and remodeling process that undergoes continuously.
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