World Journal of
Pharmaceutical and Life Sciences

ROUTINE POST OPERATIVE ANTIBIOTIC PROPHYLAXIS IS UNNECESSARY TO PREVENT PORT SITE INFECTION IN ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY FOR LOW RISK GALL STONE DISEASE: A PROSPECTIVE RANDOMIZED CLINICAL TRIAL

Dr. D. J. Bhaumik*, Dr. P. Sengupta, Dr. Gunjan Shoor and Dr. Arnab De.

ABSTRACT

Background: Cholecystitis is a global phenomenon prevailing more or less all over the world. One of the causes of increased morbidity after laparoscopic cholecystectomy has been port site infection. This study was carried out to compare the incidence of port site infections after elective laparoscopic cholecystectomy in patients receiving post op antibiotic prophylaxis to those receiving none. Methods: 100 patients undergoing elective laparoscopic cholecystectomy for low risk gall stone disease meeting the inclusion and exclusion criteria were divided into 2 groups. 50 patients allotted group I received post-operative antibiotic prophylaxis, while 50 patients in group II received none. Patients were followed postoperatively for wound infection on 10th to 14th day postoperatively. Results: There was no significant difference in the incidence of wound infection following elective laparoscopic cholecystectomy in the two groups. 4 of 50 (8%) developed wound infection in group 1 while 2 of 50 (4%) developed wound infection in group 2. Moreover, the difference in the incidences of diabetes mellitus and intraoperative bile leak in the two groups was also found to be not significant. Conclusion: The use of post-operative antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy for low risk gall stone disease does not alter the risk of port site infection.

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