Abstract
ERYTHROPOITIEN: EFFECTS, APPLICATIONS AND INDUSTRIAL PRODUCTION SYSTEMS
Muhammad Waqas*, Sikander Ali, Syed Sajid Jan and Noaman Yaseen
ABSTRACT
Human erythropoietin is a hormone primarily produced for regulating the process of red blood cell formation. The study was carried out to evaluate effects, functions, applications, future prospects and industrial production methods of this glycoprotein. Roles other than just erythropoiesis which show promising clinical scope are discussed. Pros and cons of different cultural systems for production of recombinant erythropoietin are explained and compared. At present mammalian culture systems using Chinese Hamster Ovary (CHO), Baby Hamster Kidney (BHK), Human HT1080 cell lines are the main industrial source for production of recombinant erythropoietin but other systems such as yeast and plant cell cultures do also have an immense potential which is still to be utilizable on commercial levels. Optimizations and advances in improving quality and productive outcomes are also visualized.
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