World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

SYNTHESIS, CHARACTERIZATION ANTI OXIDANT ACTIVITY OF NOVEL 1,5 BENZOTHIAZEPINES FROM CHALCONES OF 1-(2,4-DIFLUOROPHENYL) ETHANONE PRECURSOR

Ch. M. M. Prasada Rao* Y. Ranganayakulu and A. Vasu Babu

ABSTRACT

1,5 benzothaizepines heterocyclic ring system having the diverse pharmacological activities. The present work focus on synthesis of novel benzothaizepines molecules by condensation of 1-(2',4'-difluorophenyl)-3-(4"- methylphenyl)-2-propen-1-one derivatives and O-amino thiophenol in the presence piperidine and glacial acetic acid. The structures of compounds were confirmed by spectral analysis using IR, 1HNMR and Mass analysis. The biological evolution of compounds were performed for anti oxidant activity by using DPPH reagent method using standard ascorbic acid.

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