World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

BIOMARKERS IN ACUTE KIDNEY INJURY: INNOVATIVE DISCOVERIES TO APPLICATION IN CLINICAL MEDICINE

*Dr. Apeksha Niraula, Dahal K., and Mallick R.L.

ABSTRACT

Acute Kidney Injury (AKI) is a common complication in severely ill patients with a significant rise in its incidence in the past one decade. Though, there has been an increased advancement with newer treatment modalities and techniques, the morbidity and mortality rates associated with acute kidney injury is still high. Serum creatinine (SCr) and urine protein estimation is the only criteria that has been used in the diagnosis of AKI commonly till date. The use of these biomarkers has shown to perform well in patients with chronic kidney disease, but not in acute disease. Newer biomarkers has been discovered to overcome this difficulty with their own advantages and pitfalls. This review article focuses on the recent diagnostic criteria for AKI with the illustration of newer biomarkers for the early diagnosis and appropriate treatment in AKI.

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