Abstract
FORMULATION, DEVELOPMENT AND IN-VITRO EVALUATION OF ORODISPERSIBLE TABLETS OF LAMOTRIGINE
C. Murali Krishna Goud,* K. Kishor Nayak, K. Vijaya and K. Prabandha
ABSTRACT
The aim of the present work is to formulate and develop orodispersible tablets of lamotrigine using different super disintegrating agent by direct compression method. The objective of the study is to increase rapid onset of action of lamotrigine in treatment of epilepsy. The orodispersible tablets of lamotrigine were prepared by diect compression method using different concentration of sodium starch glycolate, crosscarmellose sodium, crospovidone, polyplasdone, indion. The tablet were evaluated for various parameters and results were found to be satisfactory. Total 15 formulations were prepared out of which f13, has shown good results.
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