World Journal of
Pharmaceutical and Life Sciences

DESIGN AND FORMULATION OF POLYHERBAL TABLETS CONTAINING “HIBISCUS AND GARLIC FOR THE TREATMENT OF HYPERTENSION”

J. Santhi Priya, B. Abhinaya Geethika*, D. Reshma, N. Bhavani, K. Lakshmi Nandini, Y. Vijay Kumar

ABSTRACT

Hypertension is a major global health concern and a leading risk factor for cardiovascular diseases. Herbal medicines have gained increasing attention due to their safety, efficacy, and minimal side effects compared to synthetic drugs. The present study focuses on the design and formulation of polyherbal tablets containing Hibiscus and Garlic, two medicinal plants known for their antihypertensive properties. Hibiscus is rich in flavonoids and antioxidants that help in vasodilation and reduction of blood pressure, while Garlic contains allicin which contributes to improved cardiovascular health by lowering cholesterol levels and regulating blood pressure. In this study, the herbal extracts were carefully processed and formulated into tablet dosage form using suitable excipients through standard pharmaceutical techniques. The formulated tablets were evaluated for various pre-compression and post-compression parameters such as flow properties, hardness, friability, weight variation, and disintegration time. The results indicated that the developed polyherbal tablets showed acceptable pharmaceutical characteristics and may provide a promising natural alternative for the management of hypertension. This formulation highlights the potential of combining herbal ingredients to enhance therapeutic effectiveness in treating high blood pressure.

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