World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ROLE OF AJA DUGDH NASYA IN A DRUG-RESISTANT CASE OF ARDHAVABHEDAKA (MIGRAINE): A CASE REPORT

Dr. Jinesh Kumar Jain, Dr. O. P. Dwivedi, *Dr. Neeraj Kumar Khare

ABSTRACT

Background: Ardhavabhedaka, a type of Shiro Roga described in Ayurveda, closely resembles migraine in modern medicine. Migraine is a chronic neurological disorder characterized by recurrent unilateral headaches associated with nausea, photophobia, and phonophobia. A subset of patients remains refractory to conventional pharmacological treatment, necessitating alternative therapeutic approaches. Objective: To evaluate the therapeutic efficacy of Aja Dugdh Nasya in a drug-resistant case of Ardhavabhedaka (migraine) using clinical outcome measures. Methods: A single-case clinical study was conducted on a 45-year-old female patient presenting with chronic migraine unresponsive to conventional therapy. The patient was treated with Aja Dugdh Nasya for 21 days. Assessment was performed using a standardized grading system for headache severity, frequency, duration, and associated symptoms. Results: Significant improvement was observed in headache intensity, frequency, duration, and associated symptoms such as nausea, vertigo, and photophobia. No adverse effects were reported. Conclusion: Aja Dugdh Nasya appears to be a safe and effective therapeutic modality for managing drug-resistant migraine. This study supports the potential of integrative Ayurvedic approaches in chronic neurological disorders.

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