World Journal of
Pharmaceutical and Life Sciences

A COMPARITIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF KAMPILLAKADI TAILA AND JATYADI TAILA IN THE MANAGEMENT OF DUSHTA VRANA VIS-A-VIS VENOUS ULCER.

Dr. Apoorva K.*, Dr. Duragappa Harijan

ABSTRACT

Dushta Vrana vis-a-vis Venous Ulcer is a chronic non-healing wound commonly affecting the lower limbs, accounting for 60–80% of all chronic ulcers and showing a high recurrence rate of 54–78%. Conventional management such as systemic or topical antimicrobials, hyperbaric oxygen therapy, negative pressure wound therapy and skin grafting.Skin grafting is often expensive and carries potential complications, highlighting the need for effective Ayurvedic alternatives. Dushta Vrana is treated with various methods under Shashti Upakrama, among which Taila upakrama is significant. Kampillakadi Taila, described in Gada Nigraha as having vrana shodhana and ropana properties, was evaluated in comparison with the established Jatyadi Taila from Sharangadhara Samhita. Forty diagnosed patients with Dushta Vrana vis-a-vis Venous Ulcer were randomly divided into two groups of twenty each: Group A received Kampillakadi Taila dressing and Group B received Jatyadi Taila dressing for 28 days. Assessment showed that both formulations significantly reduced itching, ulcer area, discharge, odour, and enhanced healthy granulation tissue, with results highly significant at p < 0.005. Overall, both tailas were effective, but Kampillakadi Taila demonstrated a comparatively superior impact due to its potent shodhana and ropana actions.

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