World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

INVESTIGATION OF CONSTITUENTS AND BIOLOGICAL ACTIVITY AND ANTIOXADANT AND GC-MS ANALYSIS OF OIL FROM SAUDI ARABIA SPECIES: LAVANDULA MULTIFIDA

Fatima M. Hassan*, Abdel Karim M. and Mai Makki

ABSTRACT

The present study was designed to investigate the chemical constituents of saudi Lavandula Multifida seed oil and to evaluate its potential antimicrobial activity. 50 components were detected by GC-MS analysis. major constituents are: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)- (27.11%), Eucalyptol (18.68%), 1,6-Octadien-3-ol, 3,7-dimethyl- (9.78%), Hentriacontane (8.87%) and Pentacosane (4.40%). The antimicrobial activity of the oil was evaluated via cup plate agar diffusion assay against five standard human pathogens (gram negative :staphylococcus aureus, bacillus subtilis and the fungi Candida albicans, gram positive: Escherichia coli and Pseudomonas aeruginosa. Lavandula Multifida oil showed partially active against Escherichia coli and good activity Pseudomonas aeruginosa. however, it was partially inactive against other test organisms. Percentage radical scavenging activity by samples was active.

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