World Journal of
Pharmaceutical and Life Sciences

A COMPARATIVE REVIEW ON KATUPIA GHRITA VIKESHIKA AND JATYADI GHRITA VIKESHIKA IN THE MANAGEMENT OF DUSHTA VRANA WITH SPECIAL REFERENCE TO DIABETIC FOOT ULCER

Dr. Hema M.*, Dr. Shilpa P. N.

ABSTRACT

In India, the prevalence of diabetic foot ulcers (DFUs) is significant, with studies showing rates around 6.2% to 12% among people with diabetes, and an estimated 15-25% of diabetics developing them over time, highlighting a major health burden, especially with high costs and amputation risks, influenced by longer diabetes duration, male gender, and older age. The annual incidence can range from 1.0-4.1%.Dushta Vrana (chronic non-healing ulcer) is a frequent complication in diabetes mellitus, with significant morbidity due to delayed healing, infection, and recurrence.[1] Diabetic foot ulcers are a common and serious problem in people with diabetes and are largely preventable. They cause significant suffering and reduce quality of life. Foot ulcers can lead to infection, repeated hospital admissions, limb amputation, and even death.Globally the lifetime risk of developing a foot ulcer in a person with diabetes is about 19%–34%, and this risk is increasing due to longer life expectancy and more complex diabetes. Once an ulcer develops, outcomes are poor. About 65% of patients develop another ulcer within 3–5 years, nearly 20% undergo lower-limb amputation during their lifetime, and 50%–70% die within five years after ulcer formation.[2] Among Shashti Upakramas mentioned in classics, Sarpi is having both Vrana Shodhana and Ropana properties..Sushruta mentions 14 types of Vrana Bandhana for healing purpose in different forms like Vikeshika, Kavalika, Plota, Pichu,but these bandaging techniques are not widely used in clinical practice[3] Traditional Ayurvedic formulations like Katupila Ghrita and Jatyadi Ghrita[4] are used for wound care, but comparative clinical outcomes require systematic evaluation.Here, we shall discuss about the role of Katupila Ghrita Vikeshika dressing in the Management of Dushta Vrana with Special Reference to Diabetic Foot Ulcer.

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