World Journal of
Pharmaceutical and Life Sciences

A NOVEL APPROACH IN DISORDER MANAGEMENT BY TRANSDERMAL PATCHES: A REVIEW

Anagha H. Gajare*, Shreya R. Rane, Neha A. Porwar

ABSTRACT

Drug delivery through the skin to achieve a systemic effect of a drug is commonly known as transdermal drug delivery. Transdermal drug delivery has evolved throughout time, with the development of passive and active technologies that have resulted in enhanced distribution, accuracy in drug dosage, and better fulfilment of the requirements of the individual. Transdermal patch of asenapine in schizophrenia offers another strategy for treatment to improve compliance and ease of administration. Hypertension is one of the largest deaths causing disease for the mankind which also uses transdermal patches, concentrations of polymer, plasticizer and penetrant were varied. Topical delivery methods have been used since the dawn of time, employed to cure a wide range of aliments and for aesthetic purposes. When compared to other transdermal drug delivery allows a controlled release of the medicine into patients, often by either a porous membrane or by body heat melting small layers of medication embedded in the adhesive. One of the diabetes mellitus treatments that can reduce pain is using insulin patch technology as a transdermal treatment. Transdermal delivery of Non-steroidal anti-inflammatory drugs and antiviral agents drugs has advantages of avoiding hepatic firstpass effect, gastric irritation and delivering the drug for an extended period of time at a sustained level. Vasomotor symptoms (VMS) associated with menopause can cause significant discomfort and decrease the quality of life for women in perimenopausal and post-menopausal stages of life. Hormone therapy is the mainstay of treatment for menopausal symptoms and is currently the only therapy proven effective for VMS.

[Full Text Article]   [Download Certificate]