World Journal of
Pharmaceutical and Life Sciences

PHYTOPHARMACOLOGICAL INVESTIGATION ON CRUDE DRUG FOR DIABETIC WOUND HEALING ACTIVITY

Bheem Khatarkar*, Dr. Narendra Patel

ABSTRACT

The present study demonstrates that the medicinal plant Lantana camara is a promising source of bioactive compounds with potential preventive roles in the pathogenesis of various diseases. However, the current data are insufficient to propose a definitive mechanism of action. Further phytochemical investigations are warranted to isolate and characterize the active constituents responsible for its antioxidant properties. Additionally, the possibility of synergistic interactions among these compounds merits exploration. Based on blood biochemical parameters, oral administration of Lantana camara at doses of 100 and 200 mg/kg body weight exhibited significant antidiabetic effects in streptozotocin (STZ)- induced diabetic rats. Moreover, the plant demonstrated effective wound healing properties at these doses. These findings suggest that Lantana camara not only possesses antidiabetic potential but also enhances wound healing, indicating dual therapeutic benefits. Nevertheless, further studies are required to validate these effects and elucidate the underlying mechanisms.

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