World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ERYTHEMA NODOSUM REVEALING SILENT CELIAC DISEASE IN CHILDHOOD: A CASE REPORT

S. Boujmil*, N. Seghrouchni, A. Laaraje, A. Radi, S. Ait Hmaddouch, A. Hassani, R. Abilkassem

ABSTRACT

Background: Erythema nodosum is the most frequent form of panniculitis, Its association with celiac disease remains uncommon, particularly in children. Case presentation: We report the case of a child presenting with recurrent erythema nodosum without gastrointestinal symptoms. Laboratory findings revealed severe iron deficiency despite prolonged oral supplementation. Serologic testing demonstrated elevated anti-transglutaminase IgA antibodies. Duodenal biopsy confirmed total villous atrophy with intraepithelial lymphocytosis confirming the diagnosis of coeiac disease. A gluten-free diet was introduced, leading to clinical and biological improvement. Conclusion: This case illustrates that celiac disease may present solely with extra-digestive manifestations such as erythema nodosum in children.

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