World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EVALUATION OF IN- VITRO ANTI-INFLAMMATORY ACTIVITY OF EMBLICA OFFICINALIS SEEDS

Siddharam Bagalkote*, Akshay Kumar S. N., Madiwalappa Ilkal

ABSTRACT

Emblica officinalis (Indian gooseberry, Amla), a medicinal plant rich in tannins and vitamin C, has long been used in Ayurveda for its antioxidant and therapeutic properties. The present study aimed to evaluate the in-vitro anti-inflammatory activity of ethanolic seeds extract of Emblica officinalis. Phytochemical screening confirmed the presence of carbohydrates, alkaloids, saponins, tannins, phenolic compounds, and proteins. Anti-inflammatory potential was assessed through albumin denaturation inhibition and anti-lipoxygenase assays. Results revealed that the extract exhibited concentration-dependent activity, showing significant inhibition comparable to diclofenac sodium and indomethacin. These findings suggest that Emblica officinalis seeds possess promising anti-inflammatory potential and could serve as a natural alternative in managing inflammatory conditions. However, further research is required to isolate the bioactive compounds and elucidate their mechanisms of action.

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