World Journal of
Pharmaceutical and Life Sciences

ESTIMATION OF LIPID PROFILE IN PATIENT WITH GALLSTONES

Samah Sajad Kadhim*, Fatima Hakim Obaid and Kazem Mehdi Kazem

ABSTRACT

Background and objective: The gallbladder is a small, pear-shaped organ. It is part of the biliary system, which includes ducts inside and outside the liver. It contributes to fat digestion by storing and concentrating bile. Gallbladder dysfunction leads to gallstone formation and may require surgical intervention. This study aimed to evaluate changes in lipid profiles (cholesterol, triglycerides, HDL, LDL, and VLDL) in patients with gallstones compared to healthy controls. Methods: A prospective, case-control study was conducted from February 10, 2022, to March 1, 2023. 50 randomly selected, clinically diagnosed, participants (healthy and patients with gallstones) aged 25–65 were included. Patients were divided into three age groups, with emphasis on the 40–60 age group due to its high incidence (50%). Results & conclusion: The results showed that HDL levels were higher in the control group, while total cholesterol, triglycerides, LDL, and VLDL levels were statistically significantly higher in gallstone patients (P ≤ 0.01). The results indicate a relationship between dyslipidemia and gallstone formation, supporting the importance of regular lipid monitoring in at-risk groups.

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