World Journal of
Pharmaceutical and Life Sciences

A REVIEW ON THE MICROBIAL LIPASES FOR ADVANCED INDUSTRIAL APPLICATIONS

Manam Walait, Kadija Tul Kubra, Hira Sundus and Dr. Sikander Ali*

ABSTRACT

The lipids hydrolysis is an enzyme catalyzed reaction which involves the formation of low molecular weight compounds. In processing Industry of several products, lipase is among one of the best commercial enzyme. For Lipase production, the industrially important enzymes are extracted from bacterial as well as fungal sources. However, several animals and plants can also be the source of Lipase. For development of fermentation processes, suitable thermostability, optimum pH, other physical and chemical parameters are critical. Fungi are used for high quality and quantity of Lipases but temperature stability is the only problem with it i.e. beyond 40oC it is not heat stable. Though, exceptions are always there. On the other hand, thermophilic bacterium, Bacillus sp. strain L2 produces extracellular thermostable lipase enzymes. Previously, a Bacterial species have been reported, which produce thermostable enzyme. This lipase enzyme has a capacity to withstand 70oC temperature. For Future perspective, there is need to separate microorganism species that are capable to grow at high temperature. Furthermore, their enzymes can be thermostable up to temperature of 95-100oC range. The objective of this document was literature review of lipase producing microbes by defining several substrate, its profile related to thermostability and advanced industrial application.

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