World Journal of
Pharmaceutical and Life Sciences

ALKALINE INTERVENTION: EXPLORING KSHARODAKA’S ROLE IN KELOID TREATMENT- A CASE SERIES

Dr. Shilpa P. N. and Dr. Sinchana R.*

ABSTRACT

Keloid is a chronic and recurrent fibroproliferative disorder of the skin, characterized by excessive collagen deposition that extends beyond the boundaries of the original wound. Globally, the annual incidence of keloids is estimated between 0.09% and 0.16%, with a prevalence as high as 16% in individuals with darker skin types, such as African, Asian, and Hispanic populations, Affects both sexes equally, though some studies suggest slightly higher rates in females, possibly due to higher rates of skin trauma (e.g., ear piercing, cesarean section, abdominoplasty, breast reduction surgeries etc). Age group most affected is10–30 years — the most active phase of wound healing and collagen synthesis. Keloids are notoriously stubborn to treat, often requiring a combination of therapies. Despite the availability of multiple treatment modalities, including corticosteroids, surgery, laser therapy, and cryotherapy, no definitive treatment exists, and recurrence remains common. In Ayurveda, keloid can be correlated to vranagranthi, for which Kshara therapy is a time-tested approach. Shigru (Moringa oleifera) ksharodaka, possessing Lekhana, Shothahara, and Kaphavatahara properties, is indicated in the management of abnormal growths. Herewith, we report a case series of 2 patient, presented with keloid over the anterior chest wall, who underwent shigru ksharodaka infiltration treatment administered subcutaneously. The treatment led to significant reductions in keloid size and softening of the tissue. Notably, good results were observed in terms of symptom relief, with most patients reporting significant improvement in pain, itching, and discomfort. No significant adverse effects were observed, demonstrating the safety and tolerability of the therapy.

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