World Journal of
Pharmaceutical and Life Sciences

A PROSPECTIVE OBSERVATIONAL STUDY AND EVALUATION OF ANTI DIABETIC DRUGS TREATMENT OF TYPE II DIABETES MELLITUS PATIENTS

Mohammed Zubair Ahmed*, Hajera Hafeez, Mohd. Ateeq Ur Rehman, Syed Azher Ullah Quadri, Syed Fayyazuddin, Md. Ismail Zubair, Pawan Kumar and Mohammed Majid Iqbal

ABSTRACT

The aim is to assess the safety and efficacy of anti-diabetic drugs; a prospective observational study was carried out at the department of general medicine in a tertiary care teaching hospital for a period of 6 months. For this study we selected the patients above 18 years of either sex, with co-morbidities, diabetes was included. It was observed that there was predominance of male (62%), female (38%) in the age group of <40-80 years, among that widely distributed in the age group of 51–60 years with frequency of 37%. we noted, larger numbers of patients were prescribed with metformin (22%) as OHA. It was found that majority of patients were administered with regular insulin sc (21%) as an insulin analogue, (because of co-morbid conditions, patients were often switched to insulin therapy in comparison with the metformin). Various other combinations of OHA and insulin analogues were also prescribed. The significant risk factor was found to be age (70%) followed by sedentary lifestyle (58%) and hypertension (47%). Upon analysis it is concluded that diabetes was more prevalent in the males and in the age group of 51–60 years, with majority being prescribed with metformin and regular insulin. While counselling it was recognized that the majority of patients were illiterate about the disease and counselling for the diabetes lifestyle management had a positive impact in maintaining their blood glucose levels and improved their condition.

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