World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

HEART RATE VARIABILITY AND SLEEP: A WINDOW INTO AUTONOMIC REGULATION IN HEALTH AND DISEASE

Dr. Sheffy S. Thomas and Dr. Sandhya M.*

ABSTRACT

Sleep is not merely a passive resting state but a complex physiological process marked by dynamic shifts in autonomic nervous system (ANS) activity. Heart rate variability (HRV), a non-invasive measure of autonomic modulation, reflects these changes across different sleep stages. This review discusses the physiological and pathological aspects of HRV during sleep, drawing on insights from recent studies, particularly the comprehensive review by Tobaldini et al. (2013). The paper emphasizes linear and non-linear HRV analysis techniques and explores the autonomic implications in disorders such as obstructive sleep apnea (OSA), insomnia, and restless leg syndrome (RLS).

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