World Journal of
Pharmaceutical and Life Sciences

A COMPARATIVE STUDY ON ANTIFUNGAL ACTION OF DANDRUFF SHAMPOO’S AND DIFFERENT PLANT EXTRACTS OF PUNICA GRANARUM AND RUBIA CORDIFOLIA LINN

Khushboo Minj, and Wasim Raja*

ABSTRACT

Dandruff a very common scalp disorder with high prevalence in population is caused by numerous host factors in conjunction with Malassezia furfur. Most of the commercially available anti-dandruff hair shampoos contain some form of antifungal agent(s) that appear to reduce the incidence of the disease. There are no good scientific studies done to prove the antifungal activity of commercially available hair shampoos. Dandruff, a prevalent scalp condition, results from the interplay between various host factor and Malassezia furfur. the majority of anti-dandruff hair shampoo on the market contain antifungal ingredients that effectively reduce disease occurrence. This investigation evaluated the antifungal efficacy of commercially available shampoos against a human dandruff isolate of M. furfur. The shampoos were head and shoulder, Dove, ketomac. Studies indicate that bioactive compound form plant extracts exhibit antifungal activity warranting further investigation for dandruff treatment. In this study commercially available shampoos were assessed for antifungal activity against a human dandruff isolate of M. furfur. The results demonstrated that all six of the assayed hair shampoos have some antifungal effect on growth of M. furfur. These products have poor efficacies, more side effects and give scope for recurrence of symptoms. The plant extracts were tested in different concentrations. This study held significance as it facilitated a comparative analysis of established plant products with antidandruff properties alongside commercial shampoos, highlighting their enhance efficacy at minimal concentration. The identified plant extracts can be combined to develop an efficacious polyherbal hair care product for dandruff management. These results confirm the antifungal activity of Punica granarum and Rubia cordifolia extract and support the traditional use of the plant in therapy of bacterial infection. This finding suggested the presence of antifungal activity in the tested plant material, exhibited by its bioactive compounds, and serving them as an alternative antifungal agent. This can help make a poly herbal mixture that could be incorporated in hair oil or shampoos for better anti-dandruff activity.

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