World Journal of
Pharmaceutical and Life Sciences

CONCEPTUAL STUDY ON THE EFFICACY OF ARDRAKA KSHARA AND MULAKA KSHARA IN THE MANAGEMENT OF MUTRASHMARI VIS À VIS UROLITHIASIS

*Dr. Minhaz ul Arbia and  Dr. Srinivas M asalekar

ABSTRACT

Mutrashmari
is a disease of Mutravahasrotas. It is one of the oldest diseases known to medicin e. Acharya
Sushrutha describes it as a Daruna and kashta Sadhya vyadhi and grouped it under Ashta mahagada owing to its
potentiality to disturb or hamper the structure and functions of Mutravaha srotas (urinary system), it is termed as
Antaka Pratima 1 as it gives intolerable pain and it becomes fatal if not treated timely. In Contemporary Medical
Science it is correlated to urolithiasis. It is estimated that 1 15% of individuals suffer from kidney stone formation
at some point of time during their life ti me. The prevalence of kidney stones is about 12% worldwide, 6.5% in men
and 5.1% in women 2 The treatment of Urolithiasis depends on size, position and type of calculi. However, these
are expensive, invasive and need hospitalization, and may end up in co mplications 3 It is often a recurrent and a
lifelong disease with a recurrence rate of 50% within 5 10 years and 75% within 20 years In ayurvedic classics
Acharya Sushrutha described use of kshara in taruna Avastha of mutrashmari as kshara destroys calcu li with its
chedana, bhedana, lekhana ksharana properties and prevents recurrence of the disease. Ardraka kshara 4 and
Mulaka kshara 5 mentioned in Raja Nighantu under kshara dashaka prakarana, which are having mutrala,
ashmarighna, bhedana, shoolaprasha mana, shothahara, Vedana sthapana, vatanulomana, vishodhana,
aamadoshahara properties. Here we shall discuss about the role of ardraka kshara and mulaka kshara, its potential
to disintegrate the stone and prevent its recurrence.

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