World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ANTIOXIDANT ACTIVITY OF THE SEEDS OF PRUNUS DULCIS USING DPPH ASSAY

Shalima N. K.*, Nimmi M., Dr. Biju C. R., Dr. Byju K., Neethu Dasan M., Princy C. and Dr. G. Babu

ABSTRACT

Background: Free radicals are produced in normal or pathological cell metabolism. Oxidation is essential to living organism for the production of energy to fuel for biological processes. Uncontrolled production of oxygen from free radicals leads to many diseases like cancer, atherosclerosis, cirrhosis and also aging. An antioxidant may be defined as „any substance that when present at low concentrations, compared with those of the oxidizable substrate significantly delays or inhibits oxidation of that substrate. The aim of this study is to evaluate the antioxidant activity of ethyl acetate extract of the seeds of prunus dulcis (rosaceae). Method: The ethyl acetate extract of prunus dulcis (rosaceae) were tested against antioxidant activity at various concentration using DPPH assay. Results: The results showed that the ethyl acetate prunus dulcis (rosaceae) shows significant antioxidant activity. EC50 values for chloroform extract and ethyl acetate extracts are 40.11 mg/ml and 24.10 mg/ml respectively. Conclusion: The present work revealed that prunus dulcis (rosaceae) contains some important chemical constituents which can be extracted using ethyl acetate as solvent, that can be used in future for the treatment of cancer, cirrhosis, atherosclerosis and even for aging.

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