Abstract
A COMPARATIVE STUDY ON EFFICACY AND SAFETY OF NIFEDIPINE AND LABETOLOL IN PATIENTS WITH PRE ECLAMPSIA
K. Ayesha*, Kumar Masum, Sahithi Vadde, Huda Tahera, Jagarlamudi Sai Sindhu, Bibi Hayath Anam, U. Kalyan Kumar, Rahul Tirumalasetty, Pallapati Bhagyalakshmi, Usha Mahathi, Morziul Haque, Yagvendra Pandey, Ramiz Jakir Maniyar, Shaikh Mohmed Adna ABSTRACT
Introduction: Pre-eclampsia is a leading cause of maternal and fetal morbidity and mortality that requires timely and effective blood pressure management. This study has compared the efficacy and safety of Nifedipine with that of Labetalol in reducing blood pressure in pre-eclamptic patients. Methodology: Ninety pre-eclamptic patients were randomly assigned into two groups, each containing 45 patients who received either Nifedipine or Labetalol. Baseline systolic and diastolic BP was measured; subsequently, BP was measured at 2, 4, 6, 12, 24, and 48 hours following the start of therapy. The percentage of patients achieving target BP (<140/90 mmHg) was compared between groups, and also the occurrence of side effects. All analyses were done by t-tests with p
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