World Journal of
Pharmaceutical and Life Sciences

A RESEARCH ON MEDICATED LOLLIPOP

*Shashank Lavkush Shukla, Shrinidhi Bhalchandra Raje and Prof. Bhakti Ashok Bang

ABSTRACT

Lollipops as a drug delivery form are a unique way to administer flavored medications that are often used for local effects in the mouth or throat. These lollipops, made by heating and solidifying a sucrose base, offer several advantages, including enhanced bioavailability, reduced dosage, minimized intestinal absorption, and avoidance of the metabolic process. Such characteristics make them particularly useful for increasing patient compliance and acceptance. Physical properties like thickness (12-13.2 mm) and hardness (10-11.5 kg/cm²) are critical for the quality of lollipops. In vitro drug release studies have shown that formulations such as L3, L6, and L10 provide efficient drug release within 30 minutes, with L3 being the most effective overall according to comprehensive testing. Additionally, stability studies indicated no significant changes in these formulations over a period of 90 days. These findings suggest that lollipops could be a promising method for delivering medications, particularly for mucolytic therapy in pediatric patients.

[Full Text Article]   [Download Certificate]