World Journal of
Pharmaceutical and Life Sciences

EXPLORING PSYCHIATRIC CHALLENGES AND COMORBIDITIES IN RENAL FAILURE AND DIALYSIS PATIENTS: A COMPREHENSIVE REVIEW

Vaibhavi Diwani*, Dr. Pankti Dalwadi, Dr. Hetal Gosai, Miral Maniar, Sneha Senghundar, Meet Limbachia

ABSTRACT

Patients with renal failure and dialysis have many difficulties, not only in terms of their physical health but also in
terms of their mental and overall wellbeing. This article offers a thorough analysis of the mental health problems
that dialysis patients with renal insufficiency face. The study clarifies the prevalent behavioral illnesses in patients
with chronic kidney disease (CKD) by referencing a broad range of literature sources, such as clinical trials, case
reports, and meta-analyses. Numerous studies have demonstrated the high frequency of psychological illnesses,
with anxiety and sadness being the most prevalent, among individuals receiving dialysis and renal failure. There is
also a high prevalence of other mental diseases such psychosis, cognitive impairment, drug use disorders, and sleep
problems. In patients with CKD, the chronic nature of the disease, stresses associated to treatment, co-occurring
medical illnesses, and psychosocial variables such social isolation and financial pressure are risk factors that lead
to the development of mental difficulties. In order to enhance mental health outcomes for this group, future
research efforts should concentrate on expanding our knowledge of the fundamental pathways connecting mental
illnesses and renal failure, finding fresh targets for therapy, and creating creative treatments. In addition, addressing
healthcare inequities, encouraging early identification and intervention, and improving patient education and
empowerment are essential for maximizing the provision of psychiatric care to patients on dialysis and in renal
failure.

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