World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Addanki Anusha*, Krishna Phanisri Ponnekanti, S. Rajeshwari, Madduri kavya, Vongeti Likitha, Neeraj Kulkarni and Nunavath Pavani


Solid dispersion technique is a highly efficient method for enhancing the rate at which weakly water-soluble
medicines dissolve, hence increasing their bioavailability. Water-soluble carriers are employed in the formulation
of solid dispersions to augment the pace at which poorly water-soluble drugs dissolve. The technique of dispersing
one or more active medicinal substances in a carrier at the solid state is referred to as solid dispersion. The
solubility behaviour of a medicine is a particularly difficult element to address in formulation creation, especially
when compared to traditional forms like tablets or capsules. Solid dispersion, on the other hand, offers several
advantages over these conventional dosage forms and can be created using numerous methods. This review paper
specifically examines the benefits, drawbacks, categorization, preparation methods, mechanisms, and
characterization of solid dispersions.

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