Abstract
INVITRO EVALUATION OF MIDOSTAURIN AND ITS DERIVATIVE ((3-HYDROXY MIDOSTAURIN-D5) FOR THE TREATMENT OF ADULT ACUTE MYELOID LEUKEMIA
Dr. Syed Ahmed Hussain*, Farahanaaz Begum, Juveria Gaffar, Shaik Nazma Sultana and Sara Umm E. Hani
ABSTRACT
This research paper presents the results of an experimental study investigating the effects of 3-Hydroxy Midostaurin-D5 on various cellular assays, including MTT, Tubulogenesis, Indirect Immunofluorescence, and Western Blot Analysis. The study comprises four treatment groups, including normal cells, a control cell line, a group treated with standard Midostaurin, and a group treated with 3-Hydroxy Midostaurin-D5. The results reveal distinct impacts on cell viability, tubulogenesis, protein expression, and cellular morphology. These findings contribute to the understanding of 3-Hydroxy Midostaurin-D5's potential as a therapeutic agent and its implications for future research and clinical applications.
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