Abstract
INVITRO EVALUATION OF MIDOSTAURIN AND ITS DERIVATIVE ((S)-3-HYDROXY MIDOSTAURIN) FOR THE TREATMENT OF ADULT ACUTE MYELOID LEUKEMIA
Dr. Syed Ahmed Hussain*, Farahanaaz Begum, Juveria Gaffar, Shaik Nazma Sultana and Sara Umm E. Hani
ABSTRACT
This research paper presents the results of an experimental study evaluating the effects of (S)-3-Hydroxy Midostaurin on various assays, including MTT, Tubulogenesis, Indirect Immunofluorescence, and Western Blot Analysis. Four groups were analyzed, including normal cells, a control cell line, a group treated with standard Midostaurin, and a group treated with (S)-3-Hydroxy Midostaurin. The results indicate varying degrees of impact on cell viability, tubulogenesis, protein expression, and cellular morphology. These findings shed light on the potential therapeutic effects of (S)-3-Hydroxy Midostaurin and its implications for future research and clinical applications.
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