World Journal of
Pharmaceutical and Life Sciences

REVIEW ON ANDROGRAPHIS PANICULATA (Burm. f.) Nees FOR POTENTIAL IMMUNOMODULATOR ACTIVITY IN COVID -19

Jitendra Shivankar*, Chakresh Patle, Rajesh Mujariya

ABSTRACT

The aimed of current review to COVID-19 pandemic has intensively disrupted global health, economics, and well-being. Andrographis paniculata (Burm. f.) Nees has been used as a complementary treatment for COVID-19 in several Asian countries. This review aimed to summarize the information available regarding A. paniculata and its constituents, to provide critical points relating to its pharmacological properties, safety, and efficacy, revealing its potential to serve as a source of lead compounds for COVID-19. A. paniculata and its active compounds possess favorable antiviral, anti-inflammatory, immunomodulatory, and antipyretic activities that could be beneficial for COVID-19 treatment. A. Paniculata specially target the white blood cell and inhibit the production of T-Cell result in improvement of Immune system. A. paniculata alone or in combination was superior to the placebo in reducing the severity of upper respiratory tract infection. the safety of A. paniculata, as discussed in this review, support the argument that A. paniculata is a promising natural source for drug discovery regarding COVID-19 post-infectious treatment, rather than prophylaxis.

[Full Text Article]   [Download Certificate]