World Journal of
Pharmaceutical and Life Sciences

SCIENTIFIC STUDY ON HOMO SAPIEN SKIN DE-PIGMENTARY DISORDER IN THE LIGHT OF HOMO SAPIEN GUT MICROBIOME ECOSYSTEM

Dr. S. S. Sawhney*

ABSTRACT

Introduction: Homo sapien skin depigmentary disorder among Asians, Africans, Arabians, etc at the tropics has not been seen in the light of the Homo sapien gut microbiome. So this study. Methods and material: Four volunteers: Ind223265A, Ind223265B, Ind223265C, and Ind223265D, with skin dark, skin lightly dark, skin wheatish, and skin white respectively, participatedin this study. RNA Sequencing and 16S Metagenomic Analyzer have been applied in the analysisof sterile fecal swabs of these volunteers Result: The bacterial composition and percentage of vitamin K biosynthesizing bacteria differed in the gut microbiomes of all the volunteers. In Ind 223265A, the strong vitamin K biosynthesizing bacteria: Clostridium (10%) and Flavobacterium (17%) have been identified in its gut microbiome whereas in Ind 223265B, Prevotella (73%) with the ability to biosynthesize vitamin K has been found. In Ind 223265C, moderate vitamin K biosynthesizing bacteria have been seen in his gut microbiome, while in Ind 223265D, the gut microbiome registered the absence of strong and moderate vitamin K biosynthesizing bacteria and displayed poor vitamin K biosynthesizing bacteria Conclusion: The vitamin K is the main complementary factor for the determination of Homo sapien skin pigmentary order. This study endorses the Sawhney theory of vitamin K deficiency in humans at tropics with the skin depigmentary disorder (HES Leucoderma). Probiotics of strong or moderate vitamin K biosynthesizing bacteria appear to be the only option to treat skin depigmentation disorder at the tropics.

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