Abstract
AN INTEGRATED REVIEW ON ADVANTAGES, CLASSIFICATION AND TECHNIQUES OF PREPARATION OF MICROEMULSION: A FUTURISTIC DRUG DELIVERY
Vaishali Soni, Imran Khan, Shalini Prajapati, Prateek Jain, Bhupendra Singh Thakur, Basant Khare, Arvind Singh Jadon and Anushree Jain*
ABSTRACT
The improvement of bio-availability of drugs is one of the greatest challenges in drug formulations. Among various approach microemulsion, which is a clear, stable, isotropic mixtures of oil, water and surfactant, has gained more attention due to enhanced oral bio-availability, protect labile drug, control drug release, increase drug solubility, and reduce patient variability. Microemulsions are commercially simple and convenient vehicle for delivery of medicaments which can enhance drug absorption with reduced systemic side effect. They can be used to optimize drug targeting without a concomitant increase in systemic absorption. Appropriate excipients selection and safety evaluation especially of the cosurfactants is crucial in the formulation of microemulsions. this review gives an overview of the formation, characterization of microemulsions, methods of preparation, advantages, disadvantages, classification and their application in different routes of drug delivery.
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