World Journal of
Pharmaceutical and Life Sciences

DEMOGRAPHIC & CLINICAL PROFILE OF HOSPITALIZED AND NON-HOSPITALIZED COVID-19 PATIENTS IN BANGLADESH

Md. Al-Amin Hossen, Sadia Islam, Md. Ashiqur Rahman, Md. Matiur Rahman, Md Mehedi Hasan, Md. Farhad Hossain Jony, Marzan Islam Lubaba and Arifa Akram*

ABSTRACT

Introduction: The COVID-19 pandemic emerged as a major public health emergency affecting the healthcare services all over the world. This study highlights demographic and clinical experience in hospitalized and non-hospitalized covid-19 patients in Bangladesh. Methodology: The study was conducted under Molecular Laboratory of Novus CRSL Dhaka between April 2021 September 2021. The diagnosis of SARS-CoV-2 infection was confirmed by real-time reverse transcriptase polymerase chain reaction (RT-PCR) on oropharyngeal swab and/or nasopharyngeal swabs in our laboratory. By contacting them with their contact number from the database then we collected their demographic, clinical and laboratory parameters. Results: Data of 150 both non-hospitalized and hospitalized patients with COVID-19 were recorded and analyzed. In non-hospitalized patients, the mean age of the patients was 44.42 ± 14.20 year with 84 (80.8%) male and 20 (19.2%) female. Comorbidities were present of which hypertension 40 (38.5%), diabetes 34 (32.7%), hypothyroidism 16 (15.4%) and others. A significant proportion of patients had symptomatic such as fever 96 (92.3%), dry cough 92 (88.5%), loss of taste 50 (48.07%), loss of smell 53 (50.96%) was the most common and normal laboratory parameters. Majority of the patients were managed with supportive treatment with paracetamol 40 (38.46%), antihistamine 80 (76.9%), oral vitamin-c 87 (83.65%), and antibiotics 70 (67.30%). It took an average of 12-14 days for them to become negative. And hospitalized patients, of whom 37 (71.73%) were males and 13 (28.26%) were female. Overall mean age was 45.12±13.80 years. Maximum cases (58.69%) were from age group of 20-40 year. 19 (41.30%) were smoker. They have some kind of comorbidities present like diabetes mellitus 21 (45.65%), hypertension 26 (56.52%), hyperlipidemia 8 (17.39%), hypothyroidism 2 (4.34%), coronary heart disease 10 (21.73%), chronic respiratory disease 1 (2.17%), severe disease 2 (4.34%). In addition, they have taken some medicine as per the doctors advise such as paracetamol 21 (45.65%), antihistamine 29 (63.04), oral vitamin c 32 (69.56%), antibiotics 27 (58.69%), antifungal 21 (45.6%) and oxygen therapy 7 (15.21%). Some changed laboratory parameters were observed. Conclusion: We concluded that there is no significant changes or abnormalities in non-hospitalized patients clinical and laboratory parameter reports but significant changes in hospitalized patient’s laboratory parameters. There is a warning for them which is post covid-19 fatigue.

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