World Journal of
Pharmaceutical and Life Sciences

UNDERSTANDING SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND ITS MANAGEMNT IN AYURVEDA – A REVIEW

Dr. Priyadarshini H. P.* and Dr. Abdul Khader

ABSTRACT

Immune tolerance is a process by which the immune system recognizes and accepts the self-tissues. These occur in two mechanisms they are central and peripheral mechanism. Autoimmunity is defined as the presence of immune response against the self-tissue. This is the harmless phenomenon identified by the presence of low titer autoantibodies / auto-reactive T cells. However, if these responses causes significant organ damage, this results in autoimmune diseases which are major cause of chronic morbidity and disability. Among all the types of auto immune diseases, systemic lupus erythamatoses is a rare condition which is having the prevalence rate of 6% and is more commonly occur in female of child bearing age. Systemic lupus Erythematosus (SLE) is a Systemic autoimmune disease in which organs and cells undergo damage mediated by tissue – binding autoantibodies and immune complexes. Here, in this paper SLE is correlated with Uttana and Gambhira Vatarakta based on sthana involved in pathogenesis and Raktadhika Vatarakta based on predominant doshas involved which presents the similar symptoms as that of SLE. Vatarakta is mainly caused due to Anyonya Avarana of Vata and Rakta. Hence, the first line of treatment should be Mridu shodana like Mridu Virechana, Basti (Saghrita, ksheera siddha), Bahirparimarjana chikitsa like Alepana, Parisheka, Abhyanga, Shamanaushadhi, Rasayana and Pathya – Apathya. The above mentioned treatment should be planned based on the sthana involvement. Hence, the Ayurvedic line of management is beneficial in Systemic lupus erythematosus conditions.

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