World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

CHEMISTRY AND SYNTHESIS OF CHIPPIINE-DIPPININE GROUP OF ALKALOIDS FOUND IN TABERNAEMONTANA SPECIES

*G. Pratheeksha, Dr. Pushpa Agrawal and Dr. Trilokchandran B.

ABSTRACT

The chippiine/dippinine/tronocarpine alkaloids are a group of indole alkaloids that are found in Tabernaemontana plants. They all have pentacyclic backbone structure. To date 14 alkaloids belonging to this group have been isolated. They are produced in extremely low concentrations in stem, bark and root of the plant. The chemical structure of the chippiine-dippinine alkaloids has been widely studied and various strategies for the synthesis of these alkaloids have been proposed in the past 20 years.

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