World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EQUILIBRIUM AND STABILITY ANALYSIS OF METAL CHELATES OF ND AND PR METALS WITH P CHLOROBENZALDEHYDETHIOSEMICARBAZONE SYSTEM

Dr. Gopal Chhetri*

ABSTRACT

Co-ordination compounds now days deserving attention due to their wide use in bio-chemisty.analytical chemistry and in agriculture industries(8), co-ordination compounds of thiosemicarbazone (ligand) with Nd, Pr, Gd, Eu etc shows their use as an anticancer properties(1-3) so it required more attention . In order to understand nature of bonding between metals and the ligand in solution and to determine the stability in solution study is essential and important .in present study varies parameters which are useful are calculated by using change in pH of ligand and its metal complex at 28oC and 38oC ,Formation constants, free energy change, entropy change and heat of reactions also calculate to determine the feasibility of complex formation.

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