World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Directory of Research Journals Indexing, Scholar Article Journal Index (SAJI), International Scientific Indexing ( ISI ), Scope Database, 



Nikita Panchal* and Dinesh Thakkar


Corona virus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization on March 11th 2019, and it has caused 400 million of cases and a million deaths since then. Researchers from various fields of expertise around the world are attempting to identify the novel molecules as well as most appropriate drugs, which are already known to treat other diseases which could address the process by which SARS-CoV2 invades and replicates in human cells as well as potentially improve cytokine storms and other related complications. In this article, we focus to look on the most promising drugs that could play a significant role in this treatment of COVID-19. The review discusses the currently explored molecules with a focus on RNA-dependent RNA polymerase (RdRp) inhibitors such as the nucleoside analogues remdesivir, favipiravir, and ribavirin. Inhibitors of 3C-like protease (3CLpro), papain-like protease (PLpro), and other potentially novel molecules like TMPRSS inhibitors, Inhibition of endocytosis Inhibition E, M, N & accessary proteins, and Suppression of excessive inflammatory responses, describing their potential targets, activities, clinical status, and side effects.

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