World Journal of
Pharmaceutical and Life Sciences

PSYCHOLOGICAL STRESS AND TYPE2 DIABETES MELLITUS

Premshanker Singh*, Granth Kumar, Achutya Pandey, Manoj Kumar and Vidyasagar

ABSTRACT

This study aims to analyze and compare psychological stress levels with long-term risk of type 2DM among productive The high incidence rate of Diabetes Mellitus (DM) among Asian productive age population significantly affects the quality of the human capital in this country. Thus, it is highly necessary to manage and to prevent the onset of DM by identifying its risk factors, both direct and indirect ones. One of these factors is psychological stress, which triggers increased level of the body's fight-or-flight hormone making the body release extra energy in the form of glucose and fat into cells. The long term psychological stress prevents the insulin from enabling the extra energy to be absorbed into the cells thereby leading the glucose to build up in the blood. Therefore, it is important to identify the psychological stress in the attempt to avoid the future incidence of DM. To determine the association between psychological stress and risk of type 2 DM among male and female,a prospective cohort study was conducted in 85 participants (aged 26-45 years) from rural population of north India. A single centric study was conducted at tertiary care hospital under UP University of Medical Sciences,India The Spearman rho was used to analyze the inferential statistic. Result of the study showed there was a strong relationship between psychological stress and the risk of type 2 DM at baseline (RR = 0.46 , p<.05) and the coefficient of determinant showed 22%. Same as on 2nd and 3rd measurements were found that the p- values are < .05, while the determinant coefficient were 33% and 19%, respectively. The evidence reflected that a long term stress or uncontrolled psychological stress for a sufficiently long period might disturb insuline regulation in the body, which in turn increases the risk of developing type 2 DM.

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