World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF SUDANESE DETARIUM MICROCARPUM GUILL. & PERR. (CAESALPINIOCEAE) OIL

Abdel Karim M.*, Elham A., Alla M. and Mai Mekki

ABSTRACT

The present study was designed to provide data on the constituents and antimicrobial activity of of Deterium microcarpum oil. Thirty six components were detected by GC-MS analysis. Detarium microcarpum oil was dominated by fatty acids(65.11%). Other constituents include: alcohols (8.35%), aldehydes (8.14%), hydrocarbons (6.12%), heterocycles(3.05) and ketones(0.54%).Major components of the oil are: (i) oleic Acid (9-octadecenoic acid ) - (21.44%) ii)9-octadecenoic acid methyl ester(12.79%) and iii) 9,12-octadecadienoic acid (Z,Z)-, methyl ester(11.38%).The oil has been screened for antimicrobial activity against : (Gram positive: Staphylococcus aureus and Bacillus subtitis; Gram negative: Escherichs coli and Pseudomonas aeruginosa and the fungal species Candida albicans. Detarium microcarpum oil showed significant activity against Escherichs coli and Pseudomonas aeruginosa and weak activity against Staphylococcus aureus. However, the oil was inactive against Bacillus subtilis and the fungal species Candida albicans.

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