World Journal of
Pharmaceutical and Life Sciences

PREVALENCE OF ECG ABNORMALITIES IN PEOPLE WITH TYPE 2 DIABETES: PROSPECTIVE STUDY AT TERTIARY CARE HOSPITAL FROM NORTH INDIA

Premshanker Singh*, Vikram Singh, Mridu Singh and P.K. Singh

ABSTRACT

Cardiovascular disease (CVD) accounts for the majority of deaths for people with type 2 diabetes mellitus. CVD is a broad term which includes any condition causing pathological changes in blood vessels, cardiac muscle or valves and cardiac rhythm. The electrocardiogram (ECG) offers a quick, non-invasive clinical and research screen for the early detection of CVD. Resting Electrocardiogram (ECG) is recommended in all Type2- Diabetes Mellitus(Type2-DM) with hypertension or suspected cardiovascular disease (CVD). However, knowledge on the prevalence of ECG abnormalities is incomplete. In this study, we have tried to analyse the prevalence of ECG abnormalities and their cross-sectional associations with cardiovascular risk factors in people with type2 diabetes reporting in Medical OPD(MOPD) and Medical IPD(MIPD) of Dr RML Institute of Medical Sciences, Lucknow The prevalence was calculated for the total study population (n = 4034) and the subgroup of people without a history of CVD (n = 3247). Logistic regression models were used to assess cross-sectional associations. Approximately one-third of the total population had minor (16.0%) or major (13.1%) ECG abnormalities. Of the participants without a CVD history, approximately one-quarter had minor (14.9%) or major (9.1%) ECG abnormalities and for those with hypertension or very high CVD risk, the prevalence was 27.5% and 39.6%, respectively. ECG abnormalities were significantly and consistently associated with established CVD risk factors. Resting ECG abnormalities are common in all people with type 2 diabetes (29.1%) including those without a history of CVD (24.0%) and their prevalence is related to traditional cardiovascular risk factors such as older age, male sex, hypertension, lower HDL cholesterol, higher LDL cholesterol ,higher Triglyceride,higher BMI and smoking behaviour.

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