World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EFFECT OF TINOSPORA CORDIFOLIA SUPPLEMENTATION ON BLOOD GLUCOSE AND LIPID PROFILE LEVEL OF STREPTOZOTOCIN INDUCED DIABETIC RAT

Susmita Roy*, Pratiti Ghosh and Debaprasad Sarkar

ABSTRACT

Antidiabetic therapy with drugs from natural origin is preffered over commercial drugs with long term usage, for their adverse side effects. In the present study the efficacy of different doses of T.cordifolia on blood profile was investigated in streptozotocin induced diabetic rats. Standard methodology was adopted to assess the blood biochemistry after obtaining institutional ethical committee clearence. Fasting blood glucose (FBG), lipid profile, urea and creatinine were found to decrease significantly (p<0.05) with increasing dose till 400mg/kg body weight. HDL-C level increased favourably. A significant decrease in creatinine, urea and blood urea nitrogen were also observed. These results indicate the ameliorative effect of T. cordifolia in the treatment of diabetes mellitus.

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