World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Prathiba H. D. and Chandrakant S. Karigar*


Modern human lifestyle has led to the significant reduction in physical activity, adequate exercise and balanced diet consumption. All these factors are the chief cause of worldwide epidemic of obesity and non-alcoholic fatty liver disease (NAFLD). NAFLD is not only associated with liver-related morbidity and mortality, but also with an increased risk of developing cardiovascular disease (CVDs) and Type 2 diabetes mellitus (T2DM). Obesity and NAFLD associated pathological features are together known as metabolic syndrome (MetS). MetS is considered as a primary risk factor for atherosclerotic complications and deaths. Therefore, MetS become major health problem of 21st century and the preventive strategies are very essential to cure this syndrome. The very important preventive methods include lifestyle management programs like regular exercise regimen and healthy diets which have been shown to be a beneficial option on overall metabolism of the body. The pathological hallmark of NAFLD is also linked to dyslipidemia, which is characterized by hypertriglyceridemia, low HDL-C levels, and high LDL-C levels. Lowering the triglycerides and Low-Density Lipoprotein (LDLs) levels thereby increasing the High-Density Lipoprotein (HDL) in the serum has been reported to reduce the risk of CVDs in NAFLD patients. Hence, it is important to identify early metabolic variations and to prevent these diseases and their advancement. This article aims to provide knowledge concerning the role of healthy lifestyle management, proper nutrition and adequate physical activities which have beneficial effects on human health and longevity.

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