World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Directory of Research Journals Indexing, Scholar Article Journal Index (SAJI), International Scientific Indexing ( ISI ), 

Abstract

EVALUATION OF ADVERSE DRUG REACTIONS ON ANTIRETROVIRAL THERAPY ON HIV PATIENTS

Dr. Khokan Bera*, Dr. Beduin Mahanti and Anushree Bhowmick

ABSTRACT

Antiretroviral therapy has transformed HIV into a manageable chronic disease, but antiretroviral medications have the potential to cause short-term and long-term adverse effects. Medication- related adverse effects may manifest in overt symptoms or initially only as laboratory abnormalities. The spectrum of potential antiretroviral drug toxicity is broad, including renal toxicity, mitochondrial and metabolic effects, gastrointestinal symptoms, weight gain, cardiovascular effects, hypersensitivity, skin reactions, insomnia, and neuropsychiatric manifestations. In general, newer antiretroviral medications have improved safety profiles compared with older antiretroviral medications, and this is reflected in the recommendations issued in the Adult and Adolescent ARV Guidelines. Clinicians who provide care to persons with HIV should have an understanding of the basic toxicity profile of antiretroviral medications, keeping in mind that the potential adverse effects of most antiretroviral medications are less toxic than the effects of untreated HIV. This Topic Review will explore antiretroviral-associated adverse effects by drug class and by specific drug. Issues related to drug interactions with antiretroviral medications are addressed in the Topic Review Drug Interactions with Antiretroviral Therapy.

[Full Text Article]

BEST PAPER AWARDS

World Journal of Pharmaceutical and life sciences Will give best paper award in every issue in the from of money along with certificate to promote research .

Best Article of current issue

Download Article : Click here