World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Sara Shireen* and Zeenath Unnissa


Background: Prophylactic anti-microbial is organization of an anti-microbial earlier to/or within the nonappearance of defilement of already sterile tissues or liquids. The utilize of antimicrobials for dirty and sullied methods isn't considered prophylaxis. Antibiotic prophylaxis is utilized to decrease the frequency of postoperative contaminations Anti-microbial prophylaxis reduces the frequency of surgical wound contamination. Rate of a surgical wound disease depends on various variables particular to either the method itself or the person persistent. Materials and methods: We have conducted a Prospection observational study, Litrature review. Discussion: From this study it can be revealed that among elective surgery done 84% received prophylactic antibiotics. Prophylactic antibiotic was given to 72% of clean wound 88.4% of clean contaminated wound,83.3% of infected wound and 25% of dirty wound. The results correspond with results in other studies done in the world which shows how the use of prophylactic antibiotic is inappropriate. Antibiotic usage in current surgical practice is often inappropriate, excessive, and chaotic. Antibiotic prophylaxis was given to clean wound but was not given in some clean contaminated wounds in which it was necessary. Antimicrobial use is a major determinant for the development of resistance and to optimize its effect in surgeries.

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