World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EVALUATION OF IN VITRO ANTI-UROLITHIATIC POTENTIAL OF MERREMIA TRIDENTATA (L.) HALLIER F. BY CALCIUM PHOSPHATE DISSOLUTION ASSAY

*Jisa Ann Sabu, Dr. Brijithlal N.D., Dr. Prakash G. Williams

ABSTRACT

Urolithiasis is as old as the human civilization. Ancient scientist identified the disease Urolithiasis and named it as ‘Ashmari’ which means a structure showing similarity to stone. Urolithiasis is commonly known as calculi formation. The present study was undertaken to evaluate the in vitro anti-urolithiatic activity of Merremia tridentata by calcium phosphate dissolution assay. The distilled water extract, ethanol extract, ethyl acetate extract, chloroform extract, lime juice extract and tender coconut water extract were taken for the evaluation. All the six extracts shown their effectiveness in the dissolution of calcium phosphate crystals. The tender coconut water extract was observed more effective than other extracts with a high rate of calcium phosphate dissolution. The study revealed that Merremia tridentata possess potent anti-urolthiatic activity.

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