World Journal of
Pharmaceutical and Life Sciences

CLINICAL STUDY TO EVALUATE THE EFFICACY OF UDARAPRASHAMANARTHA GUDUCHYADI KWATHA IN ALCOHOLIC LIVER DISEASE

Dr. Twinkle Gupta*

ABSTRACT

Acoholic liver disease is a result of overconsuming alcohol that damages the liver, leading to a build up of fats, inflammation and scarring. It can be fatal. The condition is a primary cause of chronic liver disease. The liver is one of the most complex organs in the human body, with over 500 functions. These include filtering out blood toxins, storing energy, making hormones and proteins, and regulating chloesterol and blood sugar. Many patients of Alcoholic Liver disease having the clinical manifestation viz. Ascites, Hepatitis etc. It was decided to work upon ALD with some Ayurvedic medicines. For that total 30 patients of ALD were selected and treated with Guduchyadikwatha (containing guduchi, amalaki and haritaki in equal proportion). The formulation was given in the dose of 20ml twice a day for the duration of one month. In the patients with raised bilirubinlevel, Katuki was added in the formulation in the appropriate quantity. All the necessary parameters along with required investigations were assessed. In the results, weight of the patients was reduced by 12.13%. The parameters like abdominal girth, distance between umblicus and pubis, distance between umblicus and right anterior superior iliac crest, distance between umblicus and left anterior superior iliac crest showed highly significant results. The investigations such as bilirubin,SGPT and SGOT also showed significant reduction in their levels. Hence , it can be said that Guduchyadi kwatha can be a good option for disease like ALD.

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