World Journal of
Pharmaceutical and Life Sciences

EFFICACY OF MISWAK AND CARDAMOM EXTRACT ON DIFFERENT CANDIDAL SPECIES: AN IN VITRO STUDY

*Dr. Reddy Lavanya, Dr. Mamatha Boringi, Dr. Nallan CSK Chaitanya, Dr. C. Tirumala Ravali, Dr. Lingam Amara Swapna, Dr. Madupu Padma Reddy

ABSTRACT

Introduction: Oral health is an integral part of overall health. Poor oral health may often lead to opportunistic infections. Among them most common is candidiasis. Antifungal activities of different plant extracts were shown to be effective against candida. This study was done with an objective, to estimate antifungal efficacy of miswak and cardamom extracts on different candidal species by comparing the growth inhibition zone with both the extracts. Materials and method: Commercially available Test organisms, of candidal species, were used for the study to which plant extracts were applied. After incubation, the zones of growth inhibition were measured in mm on agar plates with a loop technique. Results: Inhibitory effects of Miswak & Cardamom extracts against different species of candida were examined. Cardamom extract showed greater inhibitory values ranging from 20mm to 10mm as a zone of inhibition when compared with miswak which ranged from 14 to 10mm as zone of inhibition in all species other than candida albicans. Conclusion: This in vitro study showed, that homemade products such as miswak and cardamom had greater antimicrobial activity. Future studies should focus on the preparation of ointments along with clinical application in the treatment of oral candidiasis.

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